GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7116495 | 1 | rs7116495 | chr11:71762085 | FAM86C | chr11:71498557-71512276:+ | 0.32 | 3.91 | 0.000107 | Severe influenza A (H1N1) infection |
| THCA | cis | rs7107174 | 1 | rs7116611 | chr11:78030046 | NARS2 | chr11:78147017-78285909:- | -0.37 | -6.59 | 1.15E-10 | Testicular germ cell tumor |
| THCA | cis | rs2084898 | 1 | rs7116650 | chr11:120041917 | TRIM29 | chr11:119981995-120008863:- | 0.41 | 7.05 | 6.15E-12 | Stroke (pediatric) |
| THCA | cis | rs7107174 | 1 | rs7116698 | chr11:77995191 | NARS2 | chr11:78147017-78285909:- | -0.37 | -6.75 | 4.22E-11 | Testicular germ cell tumor |
| THCA | cis | rs7107174 | 1 | rs7117238 | chr11:78040259 | NARS2 | chr11:78147017-78285909:- | -0.41 | -7.95 | 1.37E-14 | Testicular germ cell tumor |
| THCA | cis | rs7118648 | 1 | rs7118648 | chr11:96108428 | CCDC82 | chr11:96085930-96123083:- | -0.26 | -4.22 | 2.92E-5 | Parkinson's disease |
| THCA | cis | rs7119 | 1 | rs7119 | chr15:77777632 | HMG20A | chr15:77713243-77777943:+ | 0.16 | 3.48 | 0.00055 | Type 2 diabetes |
| THCA | cis | rs7119 | 1 | rs7119 | chr15:77777632 | SGK269 | chr15:77400471-77577333:- | 0.16 | 5.34 | 1.47E-7 | Type 2 diabetes |
| THCA | cis | rs7107174 | 1 | rs7119933 | chr11:78049750 | NARS2 | chr11:78147017-78285909:- | -0.39 | -7.38 | 6.84E-13 | Testicular germ cell tumor |
| THCA | cis | rs2084898 | 1 | rs7119954 | chr11:120046224 | TRIM29 | chr11:119981995-120008863:- | 0.41 | 7.02 | 7.48E-12 | Stroke (pediatric) |
| THCA | cis | rs3829251 | 1 | rs7120029 | chr11:71198957 | NADSYN1 | chr11:71164217-71212579:+ | 0.2 | 4.74 | 2.85E-6 | Vitamin D levels |
| THCA | cis | rs712022 | 1 | rs712022 | chr11:22843155 | SVIP | chr11:22843600-22851382:- | -0.29 | -7.04 | 6.67E-12 | Dialysis-related mortality |
| THCA | cis | rs7927771 | 1 | rs7120333 | chr11:47817441 | C1QTNF4 | chr11:47611216-47615961:- | -0.31 | -5.38 | 1.2E-7 | Subjective well-being |
| THCA | cis | rs712039 | 1 | rs712039 | chr17:35850553 | TADA2A | chr17:35766981-35837224:+ | -0.2 | -4.75 | 2.67E-6 | Tuberculosis |
| THCA | cis | rs79243044 | 1 | rs7120668 | chr11:5567854 | UBQLNL | chr11:5535624-5537956:- | -0.28 | -6.23 | 1.05E-9 | QRS duration in Tripanosoma cruzi seropositivity |